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Tetracyclines

Organic compounds comprising a linearly fused tetracyclic backbone to which a variety of functional groups can be attached; they have an octahydrotetracene-2-carboxamide skeleton, and are known as derivatives of polycyclic naphthacene carboxamide.
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1

Rolitetracycline, MedChemExpress

MedChemExpress Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic. Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal drug and a prodrug.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 527.57
Color Light Brown
Physical Form Solid
Chemical Name or Material Rolitetracycline
Grade Research
SMILES O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@](C)(O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)NCN5CCCC5
For Use With (Application) COVID-19-immunoregulation
Percent Purity 95.0%
CAS 751-97-3
Solubility Information H2O : 10 mg/mL (18.95 mM; Need ultrasonic and warming) ∣Ethanol : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble) ∣DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H33N3O8
Formula Weight 527.57
2

Sancycline, MedChemExpress

MedChemExpress Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 414.41
Color Earth Yellow
Physical Form Solid
Chemical Name or Material Sancycline
Grade Research
SMILES O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.12%
CAS 808-26-4
Solubility Information DMSO : 8.33 mg/mL (20.10 mM; ultrasonic and warming and heat to 60°C)
Synonym Bonomycin 6-Demethyl-6-deoxytetracycline
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C21H22N2O7
Formula Weight 414.41