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Pyrazines

Aromatic organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions of the ring, making this ring symmetrical.

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1

HSR6071, MedChemExpress

MedChemExpress HSR6071, a pyrazinecarboxamide derivative, is an orally active and potent antiallergic agent. HSR6071 potently inhibits the experimental asthma in rat models.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 260.26
Color Light Yellow
Physical Form Powder
Chemical Name or Material HSR6071
Grade Research
SMILES O=C(C1=NC(N2CCCC2)=CN=C1)NC3=NN=NN3
For Use With (Application) COVID-19-immunoregulation
Percent Purity 98.51%
CAS 111374-21-1
Solubility Information H2O : 50 mg/mL (192.12 mM; ultrasonic and adjust pH to 12 with NaOH)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C10H12N8O
Formula Weight 260.26
2

Gilteritinib, MedChemExpress

MedChemExpress Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 552.71
Color Light Yellow
Physical Form Solid
Chemical Name or Material Gilteritinib
Grade Research
SMILES NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 97.77%
CAS 1254053-43-4
Solubility Information Ethanol : 100 mg/mL (180.93 mM; ultrasonic and adjust pH to 2 with HCl) ∣DMSO : 2 mg/mL (3.62 mM; Need ultrasonic)
Synonym ASP2215
Purity Grade Notes Research
Recommended Storage 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life 4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula C29H44N8O3
Formula Weight 552.71