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Benzopyrans

Organic polycyclic compounds that consist of a benzene fused with a heterocyclic pyran ring; pyran rings are six-membered non-aromatic rings with five carbon atoms, one oxygen atom, and two double bonds.

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1

Deguelin, MedChemExpress

MedChemExpress Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 394.42
Color Light Yellow
Physical Form Solid
Chemical Name or Material Deguelin
Grade Research
SMILES O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.0%
CAS 522-17-8
Solubility Information DMSO : 100 mg/mL (253.54 mM; Need ultrasonic)
Synonym (-)-Deguelin (-)-cis-Deguelin
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H22O6
Formula Weight 394.42
2

CU-CPT17e, MedChemExpress

MedChemExpress CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist that activates TLR3, TLR8, and TLR9.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 504.49
Color Light Yellow
Physical Form Solid
Chemical Name or Material CU-CPT17e
Grade Research
SMILES O=[N+]([O-])C(C=C1)=CC=C1COC2=CC(C=CC3(CCOCC3)O4)=C4C=C2OCC5=CC=C([N+]([O-])=O)C=C5
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 2109805-75-4
Solubility Information DMSO : 5 mg/mL (9.91 mM; Need ultrasonic and warming)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H24N2O8
Formula Weight 504.49
3

Iclaprim, MedChemExpress

MedChemExpress Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 354.4
Color Off-White
Physical Form Solid
Chemical Name or Material Iclaprim
Grade Research
SMILES NC1=NC=C(CC2=C3C=CC(C4CC4)OC3=C(OC)C(OC)=C2)C(N)=N1
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.49%
CAS 192314-93-5
Solubility Information DMSO : 30 mg/mL (84.65 mM; Need ultrasonic and warming)
Synonym AR-100
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H22N4O3
Formula Weight 354.4