A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
Targets 475 genes with up to 4 gRNA per gene target for a total of 1,900 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Silencer Human Drug Targets siRNA Library contains 23,745 Invitrogen™ Silencer siRNAs targeting 7,915 genes for performing RNAi screens against known human drug target genes.
The Silencer™ Select Human Ubiquitin siRNA Library contains 2,943 Invitrogen™ Silencer Select siRNA s targeting 981 genes, including ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin ligases.
The Invitrogen™ LentiArray™ Human Cancer Biology Library targets 510 genes commonly involved in the development of cancer with up to 4 gRNA per gene target (pooled in a single well) for a total of 2,040 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
Silencer™ siRNA Libraries feature combinations of Silencer™ Pre-designed siRNAs, and when available, Silencer™ Validated siRNAs, in 96-well or 384-well plates.
Targets 288 genes with up to 4 gRNA per gene target for a total of 1,152 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus
Targets 328 genes with up to 4 gRNA per gene target for a total of 1,312 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
Targets 822 genes with up to 4 gRNA per gene target for a total of 3,288 gRNAs. Libraries are delivered as 50μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.
The Silencer™ Select Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.