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Ub-K63 Mouse anti-Human, Clone: HWA4C4, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6077-80

Additional Details : Weight : 0.01000kg

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Product Code. 15287697

  • 103.00 EUR / 25µg


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Description

Description

Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Ubiquitin is a conserved 76 amino acid polypeptide and can affect proteasomal degradation of the protein it is bound to, or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the Uubiquitin pathway is important as it controls the cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after a covalent attachment of the peptide to a lysine residue of a protein, which involves three enzymatic reactions: E1, E2 and E3. The first reaction involves ubiquitin-activating enzyme. The third reaction uses enzyme ubiquitin ligase (E3) to transfer the activated ubiquitin from E2 to a lysine residue on a protein, or directly transfers the ubiquitin from E2 to the substrate.
Specifications

Specifications

Ub-K63
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P0CG47
K63-linked polyubiquitin, Lysine63-linked poly ubiquitin chain
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
HWA4C4
Unconjugated
UBB
Liquid
UBB
IgG2a
25 μg
4° C
Primary
7314
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