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U2AF1L4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Thermo Scientific PA5113684
Additional Details : Weight : 0.01000kg
Description
Immunogen sequence: KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Goat: 79%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Shows a preference for AGC or AGA. [UniProt]Specifications
| U2AF1L4 | |
| Polyclonal | |
| Unconjugated | |
| U2AF1L4 | |
| FLJ35525; MGC33901; Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1 like 4; U2 small nuclear RNA auxiliary factor 1-like 3; U2 small nuclear RNA auxiliary factor 1-like 4; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like 3; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2AF1L3; U2AF1L3V1; U2AF1L4; U2AF1-like 4; U2AF1-like protein 3; U2AF1RS3; U2AF1-RS3; U2af26 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 199746 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| Q8WU68 | |
| U2AF1L4 | |
| Synthetic peptide directed towards the N-terminal region of Human U2AF1L4 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |