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Staurosporine, MP Biomedicals™

Catalog Number p-7083134
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Quantity:
1 mg
500 μg
This item is not returnable. View return policy
62996-74-1
C28H26N4O3
466.541
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Staurosporin, Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
This item is not returnable. View return policy
62996-74-1
C28H26N4O3
466.541
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Staurosporin, Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Possesses inhibitory activity against fungi and yeasts. Staurosporine, MP Biomedicals is an antibiotic that is isolated from Streptomyces species. It is a potent inhibitor of phospholipid/Ca2+-dependent protein kinases and is used to study the involvement

Starosporin is used to study the involvement of protein kinases in signal transduction pathways. It arrests normal cells in the G1 checkpoint and is a potent inhibitor of Protein kinase C and other protein kinases in vitro and in cultured cells. It is an inducer of apoptosis in many mammalian cell types.

  • Potent inhibitor of phospolipid/calcium dependent and cyclic nucleotide dependent protein kinases
  • Useful as a tool for studies on protein phosphorylation in the regulation of cellular functions
  • Inhibits the upregulation of VEGF expression in tumor cells
  • Partially reverses MDR, sensitizing cells with MDR phenotype to cytotoxic agents
  • Inhibits Pgp phosphorylation (functional significance of Pgp phosphorylation is ill defined)
Physical Form Powder
Melting Point 237°C
Solubility Information May be reconstituted by dissolving the lyophilized reagent in DMSO (5mg/mL, clear, colorless solution), DMF, ethyl acetate (5mg/mL, clear colorless solution) or methanol or water.
Formula Weight 466.5
Percent Purity ≥98%
Quantity 500 μg
compliance-icons
Product Identifier
  • Staurosporine
Signal Word
  • Danger
Hazard Category
  • Carcinogenicity Category 1B
  • Germ cell mutagenicity Category 1B
Hazard Statement
  • H340-May cause genetic defects.
  • H350-May cause cancer.
Precautionary Statement
  • P101-If medical advice is needed, have product container or label at hand.
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
  • MIXTURE LIST-Contains : Staurosporine
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