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Staurosporine, 99+%, Thermo Scientific Chemicals

Catalog Number p-7042530
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Quantity:
1 mg
5 mg
10 mg
62996-74-1
C28H26N4O3
466.541
MFCD00077402
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
62996-74-1
C28H26N4O3
466.541
MFCD00077402
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Antibiotic AM-2282
49831000
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
  • Staurosporine has anti-cancer properties that can induce apoptosis
  • Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles

Application

  • Staurosporine is used for research on acute myeloid leukemia
  • It is suitable for research applications including cell culture and biochemistry
TRUSTED_SUSTAINABILITY
Type Staurosporine
Physical Form Powder
Melting Point 240°C to 243°C
Beilstein 1060573
Merck Index 14,8802
Solubility Information Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
Formula Weight 466.54
Percent Purity ≥99%
Color Yellow
Quantity 1 mg
Chemical Name or Material Staurosporine
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RUO – Research Use Only

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