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RASA3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA530445
Additional Details : Weight : 0.01000kg
Description
Recommended positive controls: SK-N-SH, IMR32, SK-N-AS, mouse brain. Predicted reactivity: Mouse (93%), Rat (92%), Xenopus laevis (86%), Chicken (89%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.Specifications
| RASA3 | |
| Polyclonal | |
| Unconjugated | |
| RASA3 | |
| AI326412; C86362; E130011G04; GAP1(IP4BP); GAP1-InsP4 BP; GAP1IP4BP; GAPIII; GAPIII activator 3; GTPase activating protein III; GTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding protein; ins P4-binding protein; Ins(1,3,4,5)P4-binding protein; ras GTPase-activating protein 3; Ras GTPase-activating protein III; RAS p21 protein activator 3; Rasa3; RP11-245B11.3; R-Ras gap; R-Ras GTP activating protein; R-ras GTPase activating protein; R-ras RTPase activating protein-3; scat | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 19414, 22821 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q14644, Q60790 | |
| RASA3 | |
| Recombinant fragment corresponding to a region within amino acids 583 and 834 of Human RASA3 | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |