MD-2 Mouse anti-Human, Clone: 9B4, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9928-80
Additional Details : Weight : 0.01000kg
DescriptionMD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
|PBS with 0.09% sodium azide; pH 7.2|
For Research Use Only.