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Invitrogen™ Human MAPK7 (ERK5), GST Tag Recombinant Protein

Human MAPK7 (ERK5), GST Tag Recombinant Protein

Brand:  Invitrogen™ A33362

Additional Details : Weight : 0.04500kg

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Product Code. 15960393

  • 7580.00 EUR / 1mg
Estimated Shipment: 13-03-2024
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Description

Description

  • This MAPK7 (ERK5) recombinant human protein (full length) was expressed in insect cells
  • MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family
  • It is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development
  • MAPK7 is activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) and is involved in downstream signaling processes of various receptors
  • In response to extracelluar signals, MAPK7 translocates to the cell nucleus where it regulates gene expression by phosphorylating and activating different transcription factors
  • Gene deletion of MAPK7 in mice results in defective blood vessel and cardiac development leading to embryonic lethality
  • MAPK7 has been shown to be critical for endothelial function and maintenance of blood vessel integrity
  • MAPK7 (ERK5) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z'-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_620602
114.7 kDa
MAP Kinases
Human
GST Tag
Dry Ice
Full Length, Recombinant, Active
Kinase Assay
1 mg
Full Length
Recombinant
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Insect
Liquid
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