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Invitrogen™ Human MAP4K3 (GLK), GST Tag Recombinant Protein
Human MAP4K3 (GLK), GST Tag Recombinant Protein
487.00 EUR - 7420.00 EUR
Specifications
| Gene Alias | MAP4K3, MAPKKKK3, MEKKK3, RAB8IPL1 |
|---|---|
| Protein Length | aa 1-380 |
| Species | Human |
| Recombinant | Recombinant |
| Protein Tag | GST Tag |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15458983
|
Invitrogen™
PV6349 |
10μg |
487.00 EUR
10µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
15478983
|
Invitrogen™
PV6351 |
1mg |
7420.00 EUR
1mg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
15468983
|
Invitrogen™
PV6350 |
100 μg |
1656.00 EUR
100µg |
Estimated Shipment: 07-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
MAP4K3 is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-alpha and can lead to the activation of the JNK signaling pathway. MAP4K3 can directly activate PKC-Θ, during TCR signaling and people with systemic lupus erythematosus show considerable enhanced MAP4K3 expression and activation of PKC-Θ, and the kinase IKK in T cells. MAP4K3 can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Specifications
| MAP4K3, MAPKKKK3, MEKKK3, RAB8IPL1 | |
| Human | |
| GST Tag |
| aa 1-380 | |
| Recombinant |