Epredia™ Lab Vision™ Laminin Ab-1 Rabbit Polyclonal Antibody with BSA and azide

Description

Extracellular matrix (ECM) surrounds and separates most tissue compartments, determines tissue architecture and dynamically interacts with its surrounding cells. The basement membrane is a part of the ECM and is composed of collagens, proteoglycans, elastin and several glycoproteins of which laminin is the most abundant. Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains Dystroglycan is a major laminin receptor in muscle and epithelia, and nidogen is a high-affinity laminin-binding protein important for basement-membrane assembly.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Laminin isolated from a rat yolk sac tumor cell line

Positive Control: Skin, Lung, Kidney or Tonsil

Cellular Localization: Basement membrane Ab-1 labels basement membrane surrounding normal vessels, glands, muscles, nerves, fat and deciduas cells separating these from abutting connective tissues.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)