missing translation for 'onlineSavingsMsg'
Learn More

Integrin beta 5 Mouse anti-Hamster, Human, Mouse, Clone: KN52, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0497-82

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15287007

  • 127.00 EUR / 100µg


In Stock 9
Add to basket

Description

Description

Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell-surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in-groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N-terminal extracellular domain that binds the ECM ligand and a small C-terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.
Specifications

Specifications

Integrin Beta 5
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O70309, P18084
CD61, GP3A, GPIIIa
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Hamster, Human, Mouse
Flow Cytometry
KN52
Unconjugated
ITGB5
Liquid
ITGB5
IgG1, kappa
100 μg
4° C
Primary
100765378, 16419, 3693
Videos
Documents

For Research Use Only.