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Integrin alpha 4 beta 7 (LPAM-1) Rat anti-Mouse, PE, Clone: DATK32 (DATK-32), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5887-83

Additional Details : Weight : 0.25000kg

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Product Code. 15258879

  • 261.00 EUR / 200µg


Estimated Shipment date
from Supplier 30-09-2019
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Description

Description

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Specifications

Specifications

Integrin alpha 4 beta 7 (LPAM-1)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P26011, Q00651
ITGB7, Gut homing receptor beta subunit, Integrin alpha-4/beta-7, Peyer patches-specific homing receptor LPAM-1, Itga4
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
DATK32 (DATK-32)
PE
Itga4
Liquid
Itga4, Itgb7
IgG2a, kappa
200 μg
4° C, store in dark, DO NOT FREEZE!
Primary
16401, 16421
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For Research Use Only.