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IL-23 p19 Mouse anti-Mouse, Clone: 5B2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7233-81

Additional Details : Weight : 0.01000kg

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Product Code. 15258047

  • 128.00 EUR / 50µg


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Description

Description

Applications Tested: The 5B2 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-23 (p19/p40) protein levels in combination with the biotinylated (p40-specific) C17.8 antibody (13-7123) for detection and recombit mouse IL-23 (14-8231) as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1-4 µg/mL. A standard curve consisting of doubling dilutions of the recombit standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate. For specific neutralization of mouse IL-23 protein activity (with no effect on IL-12 p70), the functional grade purified G23-8 antibody is recommended (cat No.16-7232). Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Specifications

Specifications

IL-23 p19
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9EQ14
IL-23, IL-23A, IL23P19, MGC79388, P19, SGRF
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
ELISA
5B2
Unconjugated
Il23a
Liquid
Il23a
IgG2b, kappa
50 μg
4° C
Primary
83430
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