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IL-20RB Monoclonal Antibody (20RNTC), eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-1206-82
176.00 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Additional Details : Weight : 0.01000kg
Description
Description: This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi. Applications Reported: This 20RNTC antibody has been reported for use in immunocytochemistry, immunoblotting (WB) and flow cytometric analysis. Applications Tested: This 20RNTC antibody has been tested by immunofluorescent staining and flow cytometric analysis of fixed and permeabilized A375 cells. This can be used between 1-10 μg/mL. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009].Specifications
IL-20RB | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
Q6UXL0 | |
Il20rb | |
Affinity chromatography | |
RUO | |
213208, 53833 | |
4° C | |
Liquid |
Flow Cytometry, Immunocytochemistry, Western Blot | |
20RNTC | |
Unconjugated | |
Il20rb | |
AV228068; DIRS1; Fibronectin type III domain containing 6; FNDC6; Gm186; IL-20 receptor subunit beta; IL20R2; IL-20R2; IL20RB; IL-20RB; IL-20R-beta; interleukin 20 receptor beta; interleukin 20 receptor beta subunit; interleukin 20 receptor subunit beta; interleukin-20 receptor II; interleukin-20 receptor subunit beta; RGD1566151; UNQ557/PRO1114 | |
Rat | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG2a κ |
For Research Use Only.