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IL-2 Monoclonal Antibody (JES6-5H4), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
120.00 EUR - 283.00 EUR
Specifications
Antigen | IL-2 |
---|---|
Clone | JES6-5H4 |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15392060
|
Affymetrix eBioscience
53-7021-82 |
100 μg |
283.00 EUR
100µg |
Estimated Shipment: 14-05-2024 Log in to see stock. |
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15382060
|
Affymetrix eBioscience
53-7021-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: The JES6-5H4 antibody has been reported useful for ELISA, ELISPOT, neutralization, and intracellular staining for flow cytometric analysis. Applications Tested: The Alexa Fluor® 488 JES6-5H4 antibody has been tested by intracellular staining and flow cytometric analysis and can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.Specifications
IL-2 | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
P04351 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
JES6-5H4 | |
Flow Cytometry | |
Alexa Fluor 488 | |
Rat | |
Mouse | |
16183 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.