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IFN beta Mouse anti-Human, Functional Grade, Clone: A1 (IFNb), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-9978-81

Additional Details : Weight : 0.01000kg

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Product Code. 15258847

  • 155.00 EUR / 50µg


Estimated Shipment date
from Supplier 24-07-2019
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Description

Description

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Specifications

Specifications

IFN beta
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P01574
IFNB1
IgG1, kappa
50 μg
4° C
Primary
3456
Functional Assay, Neutralization
A1 (IFNb)
Functional Grade
IFNB1
Liquid
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
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