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GAPDHS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13937-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the beta-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.Specifications
GAPDHS | |
Polyclonal | |
Unconjugated | |
GAPDHS | |
GAPD2, GAPDH 2, GAPDH2, GAPDHS, GAPDS, HSD 35 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14447, 26330, 66020 | |
-20°C | |
Liquid |
Western Blot | |
0.43 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O14556, Q64467, Q9ESV6 | |
Gapdhs | |
GAPDHS Fusion Protein Ag4988 | |
20 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |