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FceR1 alpha Mouse anti-Human, Biotin, Clone: AER-37 (CRA1), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5899-80

Additional Details : Weight : 0.25000kg

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Product Code. 15259919

  • 130.00 EUR / 25µg


Estimated Shipment date
from Supplier 20-11-2019
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Description

Description

FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.
Specifications

Specifications

FceR1 alpha
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P12319
RP11-550P17.3, FCE1A, FcERI
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
AER-37 (CRA1)
Biotin
FCER1A
Liquid
FCER1A
IgG2b, kappa
25 μg
4° C, do not freeze
Primary
2205
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