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FceR1 alpha Armenian Hamster anti-Mouse, Functional Grade, Clone: MAR-1, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5898-85

Additional Details : Weight : 0.01000kg

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Product Code. 15258687

  • 351.00 EUR / 500µg


Estimated Shipment date
from Supplier 26-07-2019
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Description

Description

Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.
Specifications

Specifications

FceR1 alpha
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P20489
RP11-550P17.3, FCE1A, FcERI
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Neutralization
March1
Functional Grade
Fcer1a
Liquid
Fcer1a
IgG
500 μg
4° C
Primary
14125
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