Learn More
Cytokeratin 19 Monoclonal Antibody (BA17), eFluor™ 570, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 41-9898-82
Additional Details : Weight : 0.25000kg
Description
Description: This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44-kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin. Applications Reported: This BA17 antibody has been reported for use in immunohistochemical staining and immunocytochemistry. Applications Tested: This BA17 antibody has been tested by immunocytochemistry on fixed and permeabilized MCF7 cells and can be used at less than or equal to 20 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filter Recommendation: When using this eFluor™ 570 antibody conjugate, we recommend a filter that will capture the 570 emission wavelength (for example, Excitation 545/25, 565LP, Emission 605/70). A standard Alexa Fluor™ 555 or TRITC filter is acceptable. Excitation: 555 nm; Emission: 570 nm
Cytokeratin 19 Monoclonal antibody specifically detects Cytokeratin 19 in Human samples. It is validated for Immunocytochemistry, Immunohistochemistry.Specifications
Cytokeratin 19 | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P08727 | |
KRT19 | |
Affinity chromatography | |
RUO | |
3880 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Immunocytochemistry, Immunohistochemistry | |
BA17 | |
eFluor 570 | |
KRT19 | |
40-kDa keratin intermediate filament; AI663979; C K1CS; CK 19; CK19; CK-19; cytokeratin 19; cytokeratin-19; EndoC; K19; K1CS; Ka19; keratin 19; keratin 19, type I; keratin complex 1, acidic, gene 19; keratin, type I cytoskeletal 19; keratin, type I, 40-kd; keratin-19; Krt-1.19; Krt1-19; Krt19; LOC100344434; MGC15366; Type I keratin Ka19 | |
Mouse | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 κ |
For Research Use Only.