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CD9, clone: eBioKMC8 (KMC8), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0091-85

Additional Details : Weight : 0.01000kg

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Product Code. 15286787

  • 220.00 EUR / 500µg


Estimated Shipment date
from Supplier 30-10-2018
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Description

Description

Description: The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on naive T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcgammaRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability.Applications Reported: This eBioKMC8 (KMC8) antibody has been reported for use in flow cytometric analysis, and immunoblotting (WB) (non-reducing).Applications Tested: This eBioKMC8 (KMC8) antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD9
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P40240
5H9, BA2, BTCC-1, DRAP-27, GIG2, MIC3, MRP-1, P24, TSPAN-29
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry, Western Blot
eBioKMC8 (KMC8)
Unconjugated
Cd9
Liquid
Cd9
IgG2a, kappa, kappa
500μg
Store at 2-8°C.
Primary
12527
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