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CD85k (ILT3) Mouse anti-Human, Functional Grade, Clone: ZM4.1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5139-85

Additional Details : Weight : 0.01000kg

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Product Code. 15258637

  • 336.00 EUR / 500µg


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Description

Description

Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Specifications

Specifications

CD85k (ILT3)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q8NHJ6
GP49B2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Functional Assay, Neutralization
ZM4.1
Functional Grade
LILRB4
Liquid
LILRB4
IgG1
500 μg
4° C
Primary
11006
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