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CD71 (Transferrin Receptor) Mouse anti-Human, Biotin, Clone: OKT9 (OKT-9), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0719-80

Additional Details : Weight : 0.25000kg

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Product Code. 15289619

  • 72.00 EUR / 25µg


Estimated Shipment date
from Supplier 22-07-2019
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Description

Description

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregcy, irritable bowel syndrome and in HIV patients.
Specifications

Specifications

CD71 (Transferrin Receptor)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P02786
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
OKT9 (OKT-9)
Biotin
TFRC
Liquid
TFRC
IgG1, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
7037
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For Research Use Only.