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CD70 Monoclonal Antibody (FR70), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
104.00 EUR - 352.00 EUR
Specifications
Antigen | CD70 |
---|---|
Clone | FR70 |
Concentration | 1 mg/mL |
Applications | Flow Cytometry, Functional Assay, Neutralization |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15278497
|
Affymetrix eBioscience
16-0701-81 |
50 μg |
104.00 EUR
50µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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15288497
|
Affymetrix eBioscience
16-0701-82 |
100 μg |
177.00 EUR
100µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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15298497
|
Affymetrix eBioscience
16-0701-85 |
500 μg |
352.00 EUR
500µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: The FR70 monoclonal antibody reacts with mouse CD70, a 30-33 kDa type II transmembrane glycoprotein. CD70 is a member of the TNF family and is expressed by activated mouse T and B lymphocytes. Interaction of CD70 with CD27, its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. Applications Reported: The FR70 antibody has been reported for use in flow cytometric analysis. FR70 has also been reported in blocking of CD70 in vitro . Applications Tested: The FR70 antibody has been tested by flow cytometric analysis of LPS-stimulated mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.Specifications
CD70 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative; pH 7.2 | |
CD27 ligand; Cd27l; CD27-L; CD27LG; CD70; CD70 antigen; Cd70 molecule; Ki-24 antigen; surface antigen CD70; Tnfsf7; TNLG8A; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7 | |
Cd70 | |
Primary | |
4° C | |
Cd70 |
FR70 | |
Flow Cytometry, Functional Assay, Neutralization | |
Functional Grade | |
Rat | |
Mouse | |
O55237 | |
21948 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.