CD66e (CEA), clone: CB30, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-0669-80
Additional Details : Weight : 0.01000kg
DescriptionDescription: The monoclonal antibody CB30 recognizes human CD66e, also known as CEA (carcinoembryonic antigen) and CEACAM5. As a member of the immunoglobulin superfamily, it is large GPI-linked glycosylated protein with a molecular weight about 200 kDa. It is expressed mainly on epithelial cells and on a variety of tumors of the gastrointestinal, respiratory and genitourinary tracts. CD66e has been shown to function in cell adhesion and migration via homophilic and heterophilic interactions with NCA (non-specific cross-reacting antigen also known as CEACAM6 and CD66c). Overexpression is correlated with tumor invasiveness and is therefore used as a clinical marker.Applications Reported: This CB30 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining.Applications Tested: This CB30 antibody has been tested by immunohistochemistry and by western blot on cell lysates prepared from MCF7 cells. This antibody can be used at less than or equal to 1 μg/mL for immunoblotting and less than 10 μg/mL for IHC. It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|meconium antigen 100, Carcinoembryonic Antigen, CD66e|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|IgG1, kappa, kappa|
|Store at 2-8°C.|
For Research Use Only.