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CD66e (CEA), clone: CB30, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0669-80

Additional Details : Weight : 0.01000kg

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Product Code. 15287047

  • 88.00 EUR / 25µg


Estimated Shipment date
from Supplier 30-10-2018
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Description

Description

Description: The monoclonal antibody CB30 recognizes human CD66e, also known as CEA (carcinoembryonic antigen) and CEACAM5. As a member of the immunoglobulin superfamily, it is large GPI-linked glycosylated protein with a molecular weight about 200 kDa. It is expressed mainly on epithelial cells and on a variety of tumors of the gastrointestinal, respiratory and genitourinary tracts. CD66e has been shown to function in cell adhesion and migration via homophilic and heterophilic interactions with NCA (non-specific cross-reacting antigen also known as CEACAM6 and CD66c). Overexpression is correlated with tumor invasiveness and is therefore used as a clinical marker.Applications Reported: This CB30 antibody has been reported for use in flow cytometric analysis, immunoblotting (WB), and immunohistochemical staining.Applications Tested: This CB30 antibody has been tested by immunohistochemistry and by western blot on cell lysates prepared from MCF7 cells. This antibody can be used at less than or equal to 1 μg/mL for immunoblotting and less than 10 μg/mL for IHC. It is recommended that this antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD66e (CEA)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P06731
meconium antigen 100, Carcinoembryonic Antigen, CD66e
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
CB30
Unconjugated
CEACAM5
Liquid
CEACAM5
IgG1, kappa, kappa
25μg
Store at 2-8°C.
Primary
1048
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