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CD45RB Rat anti-Mouse, FITC, Clone: C363.16A, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-0455-82

Additional Details : Weight : 0.25000kg

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Product Code. 15288099

  • 79.75 EUR / 100µg


Estimated Shipment date
from Supplier 22-07-2019
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Description

Description

CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed in microglia and inflammatory cells. In addition to involvement in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is involved in DNA fragmentation during apoptosis. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells.
Specifications

Specifications

CD45RB
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P06800
B220, CD45, CD45R, GP180, LCA, LY5, T200
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
C363.16A
FITC
Ptprc
Liquid
Ptprc
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
19264
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For Research Use Only.