missing translation for 'onlineSavingsMsg'
Learn More

CD41a Mouse anti-Human, Clone: HIP8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0419-82

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15256947

  • 108.00 EUR / 100µg


Estimated Shipment date
from Supplier 01-07-2019
Add to basket

Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41a
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P08514
BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, GPalpha IIb, integrin alpha-IIb, platelet fibrinogen receptor, alpha subunit, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, ITGA2B
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunohistochemistry
HIP8
Unconjugated
ITGA2B
Liquid
ITGA2B
IgG1, kappa
100 μg
4° C
Primary
3674
Videos
Documents

For Research Use Only.