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CD273 (B7-DC) Rat anti-Mouse, FITC, Clone: 122, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-9972-82

Additional Details : Weight : 0.25000kg

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Product Code. 15258399

  • 190.00 EUR / 100µg


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Description

Description

2 μm post-manufacturing filtered. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Specifications

Specifications

CD273 (B7-DC)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9WUL5
B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
122
FITC
Pdcd1lg2
Liquid
Pdcd1lg2
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
58205
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For Research Use Only.