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CD273 (B7-DC) Mouse anti-Human, Biotin, Clone: MIH18, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5888-80

Additional Details : Weight : 0.25000kg

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Product Code. 15259899

  • 81.25 EUR / 25µg


Estimated Shipment date
from Supplier 28-10-2019
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Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.
Specifications

Specifications

CD273 (B7-DC)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9BQ51
B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MIH18
Biotin
PDCD1LG2
Liquid
PDCD1LG2
IgG1, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
80380
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For Research Use Only.