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CD21/CD35 Rat anti-Mouse, PE, Clone: eBio8D9 (8D9), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0211-83

Additional Details : Weight : 0.25000kg

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Product Code. 15288479

  • 264.00 EUR / 200µg


Estimated Shipment date
from Supplier 22-07-2019
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Description

Description

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintece of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands. CD35 encodes a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.
Specifications

Specifications

CD21/CD35
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P19070
EBV receptor, complement C3d receptor, complement receptor type 2, epstein-Barr virus receptor, C3-binding protein, C3b/C4b receptor, CD35 antigen, Knops blood group antigen, complement component receptor 1, complement receptor type 1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
eBio8D9 (8D9)
PE
Cr2
Liquid
Cr2
IgG2a, lambda
200 μg
4° C, store in dark, DO NOT FREEZE!
Primary
12902
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For Research Use Only.