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CD196 (CCR6) Mouse anti-Human, Clone: R6H1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1969-82

Additional Details : Weight : 0.01000kg

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Product Code. 15257287

  • 172.00 EUR / 100µg


Estimated Shipment date
from Supplier 30-07-2019
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Description

Description

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor. Another member of the TRAIL receptor family was more recently identified and designated DcR2, TRAIL-R4, or TRUNDD. DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis.
Specifications

Specifications

CD196 (CCR6)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P51684
BN-1, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunoprecipitation, Western Blot
R6H1
Unconjugated
CCR6
Liquid
CCR6
IgG1, kappa
100 μg
4° C
Primary
1235
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For Research Use Only.