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CD153 Rat anti-Mouse, PE, Clone: RM153, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-1531-82

Additional Details : Weight : 0.25000kg

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Product Code. 15288689

  • 173.00 EUR / 100µg


Estimated Shipment date
from Supplier 29-05-2019
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Description

Description

The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin′s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin′s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin′s lymphomas (including Burkitt′s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
Specifications

Specifications

CD153
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P32972
CD153; CD153 antigen; CD30 antigen ligand; CD30 ligand; CD30-L; CD30L; CD30LG; TNFSF8; tumor necrosis factor (ligand) superfamily member 8; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3A; tumor necrosis factor ligand superfamily member 8
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
RM153
PE
Tnfsf8
Liquid
Tnfsf8
IgG2b, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
21949
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