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CD11c, Alexa Fluor 488, clone: N418, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-0114-82

Additional Details : Weight : 0.25000kg

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Product Code. 15391980

  • 199.00 EUR / 100µg

In Stock 2
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Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.Applications Reported: This N418 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections.Applications Tested: This N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. This N418 antibody has been tested by immunohistochemistry of frozen mouse tissue and can be used at less than or equal to 10 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.


Alexa Fluor 488
Armenian Hamster
Store at 2-8°C. Do not freeze. Light-sensitive material.
Immunohistochemistry (Frozen)
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha

For Research Use Only.