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CD107b (LAMP-2), clone: eBioH4B4 (H4B4), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1078-82

Additional Details : Weight : 0.01000kg

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Product Code. 15287167

  • 97.25 EUR / 100µg


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Description

Description

Description: The eBioH4B4 monoclonal antibody reacts with human CD107b, also known as lysosomal-associated membrane protein-2 (LAMP-2). CD107b is a highly glycosylated, type I transmembrane protein of approximately 105 kDa. It is expressed intracellularly in lysosomal/endosomal membranes in nearly all cells. It is also expressed on the surface of degranulating T cells (to a lesser extent than CD107a) and activated platelets as well as some cancer cells. In humans, mutations in CD107b results in a lysosomal glycogen storage disorder, known as Danon disease.Applications Reported: Purified anti-human CD107b (LAMP-2) has been reported for use in flow cytometric analysis. It has also been reported for use in surface staining in a flow cytometric based degranulation assay. (Fluorochrome conjugated eBioH4B4 (H4B4) is recommended for use in flow cytometry.).Applications Tested: This eBioH4B4 (H4B4) antibody has been tested by intracellular staining and flow cytometric analysis of Jurkat cell line. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. This antibody has also been tested by immunoblotting at 1 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD107b (LAMP-2)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P13473
RP23-193O17.2, CD107b, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, Mac3
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Western Blot
eBioH4B4 (H4B4)
Unconjugated
LAMP2
Liquid
LAMP2
IgG1, kappa, kappa
100μg
Store at 2-8°C.
Primary
3920
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