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CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-1051-81

61.00 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.25000kg

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Product Code. 15279669

  • 91.50 EUR / 50µg
Estimated Shipment: 08-05-2024
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Description

Description

Description: The MJ7/18 monoclonal antibody reacts with the mouse CD105 molecule, also known as Endoglin. This 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Applications Reported: The MJ7/18 antibody has been reported for use in flow cytometric analysis. Applications Tested: The MJ7/18 antibody has been tested by flow cytometric analysis of bEnd.3 cells and mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
Specifications

Specifications

CD105 (Endoglin)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q63961
ENG
Affinity chromatography
RUO
13805
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
MJ7/18
Biotin
ENG
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Rat
50 μg
Primary
Mouse
Antibody
IgG2a κ
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