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Bcl-XL Mouse anti-Human, Clone: 4C12A6, Proteintech
Mouse Monoclonal Antibody
140.00 EUR - 399.00 EUR
Specifications
Antigen | Bcl-XL |
---|---|
Clone | 4C12A6 |
Concentration | 1 mg/mL |
Applications | Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16837525
|
Proteintech
66020-1-IG-20UL |
20 μL |
140.00 EUR
20µL |
Estimated Shipment: 04-06-2024 Log in to see stock. |
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16827525
|
Proteintech
66020-1-IG-150UL |
150 μL |
399.00 EUR
150µL |
Estimated Shipment: 04-06-2024 Log in to see stock. |
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Description
BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.Specifications
Bcl-XL | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Apoptosis regulator Bcl X, BCL2L1, Bcl-XL | |
BCL2L1 | |
IgG2b | |
Protein A | |
Antibody |
4C12A6 | |
Immunofluorescence, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry | |
Unconjugated | |
Mouse | |
Human | |
Q07817 | |
598 | |
Bcl-XL Fusion Protein Ag18037 | |
Primary | |
-20°C | |
BCL2L1 |