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  6. 6-Chloropurine riboside, 98%

6-Chloropurine riboside, 98%

Product Code. 15466018
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Quantity:
1 g
5 g
Unit Size:
1g
5g
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Product Code. 15466018

Brand: Thermo Scientific Alfa Aesar H59634.03

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Description

CAS: 5399-87-1 | C10H11ClN4O4 | 286.67 g/mol

6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-Chloropurine riboside is used to study the kinetics and substrate specificity of adenosine deaminase. 6-Chloropurine riboside is benzoylated to facilitate synthesis of nucleoside derivatives such as 9-(2,3-Di-deoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine. It , especially after phosphorylation to NMP, NDP or NTP, is used as a purine substrate analogue in studies with enzymes such as Inosine monophosphate dehydrogenase (IMPDH); bacteriophage T4 RNA-ligase (EC 6.5.1.3) and pancreatic fibonuclease A.

Solubility
Soluble in water. (10.6 mg/mL)

Notes
Keep away from heat and humidity. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 5399-87-1
Molecular Formula C10H11ClN4O4
Molecular Weight (g/mol) 286.67
MDL Number MFCD00005738
InChI Key XHRJGHCQQPETRH-UHFFFAOYNA-N
Synonym 6-chloropurine riboside, chloropurine riboside, 2r,3r,4s,5r-2-6-chloro-9h-purin-9-yl-5-hydroxymethyl tetrahydrofuran-3,4-diol, 6-chloropurine ribonucleoside, 6-chloropurine-9-riboside, 6-chloro-9-ribofuranosyl-9h-purine, 9h-purine, 6-chloro-9-ribofuranosyl, 6-chloropurineriboside, 6-chloro-9-beta-d-ribofuranosyl-9h-purine, 6-chloronebularine
PubChem CID 93003
IUPAC Name (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
SMILES OCC1OC(C(O)C1O)N1C=NC2=C(Cl)N=CN=C12

Specifications

Melting Point 158°C to 162°C (decomposition)
Color White
Quantity 1 g
Beilstein 40573
Solubility Information Soluble in water. (10.6mg/mL)
Formula Weight 286.67
Percent Purity 98%
Physical Form Powder
Chemical Name or Material 6-Chloropurine riboside

RUO – Research Use Only

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