A broad array of cell-based assays designed for use with a variety of live cell experiments and procedures. Ideal for molecular and cell biology research applications.
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
The BacMam Histone H3K27me3 Cellular Assay is a high-throughput screening (HTS) compatible TR-FRET assay for the interrogation of trimethylation at lysine 27 on histone H3 in a cellular format.
The Tango™ EDG2-bla U2OS cells contain the human Endothelial Differentiation Gene 2 (EDG2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The Tango™ CCR2-bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 2 (CCR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
ER beta-UAS-bla GripTite™ 293 cells contain the ligand-binding domain (LBD) of the human Estrogen receptor beta (ER beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla GripTite™ 293 cell line.
GeneBLAzer™ EDNRA HEK 293T DA (Division Arrested) cells and EDNRA-NFAT-bla HEK 293T cells contain the human Endothelin type A (EDNRA) receptor stably integrated into the CellSensor™ NFAT-bla HEK 293T cell line.
GeneBLAzer™ PROKR2-Gqi5-NFAT-bla CHO-K1 cells contain the human prokineticin receptor 2 (PROKR2), stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla CHO-K1 cell line.
The Tango™ F2RL1-bla U2OS cells contain the human Coagulation factor II (thrombin) receptor-like 1 (F2RL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The Tango™ H4-bla U2OS cells contain the human Histamine Receptor 4 (H4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
CYP1A1 is an extrahepatic cytochrome P450 with broad substrate specificity involved in the metabolism of numerous potentially toxic and carcinogenic compounds.