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AF-DX 384, Tocris Bioscience™

Catalog Number 18045792

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Quantity:

50 mg

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CAS	118290-26-9
Molecular Formula	C27H38N6O2
Molecular Weight (g/mol)	478.641
InChI Key	MZDYABXXPZNUCT-UHFFFAOYSA-N
Synonym	af-dx 384, afdx384, af-dx-384, 3h af dx-384, 3h af-dx 384, n-2-2-dipropylamino methyl piperidin-1-yl ethyl-6-oxo-5h-benzo e pyrido 3,2-b 1,4 diazepine-11 6h-carboxamide, n-2-2-dipropylamino methyl-1-piperidinyl ethyl-5,6-dihydro-6-oxo-11h-pyrido 2,3-b 1,4 benzodiazepine-11-carboxamide, afdx-384, n-2-2-dipropylamino methyl piperidin-1-yl ethyl-6-oxo-5h-pyrido 2,3-b 1,4 benzodiazepine-11-carboxamide, d06pvq
PubChem CID	119357
IUPAC Name	N-[2-[2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
SMILES	CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4

This item is not returnable. View return policy

CAS	118290-26-9
Molecular Formula	C27H38N6O2
Molecular Weight (g/mol)	478.641
InChI Key	MZDYABXXPZNUCT-UHFFFAOYSA-N
Synonym	af-dx 384, afdx384, af-dx-384, 3h af dx-384, 3h af-dx 384, n-2-2-dipropylamino methyl piperidin-1-yl ethyl-6-oxo-5h-benzo e pyrido 3,2-b 1,4 diazepine-11 6h-carboxamide, n-2-2-dipropylamino methyl-1-piperidinyl ethyl-5,6-dihydro-6-oxo-11h-pyrido 2,3-b 1,4 benzodiazepine-11-carboxamide, afdx-384, n-2-2-dipropylamino methyl piperidin-1-yl ethyl-6-oxo-5h-pyrido 2,3-b 1,4 benzodiazepine-11-carboxamide, d06pvq
PubChem CID	119357
IUPAC Name	N-[2-[2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
SMILES	CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4

Description

Potent M2/M4 antagonist

Potent M2/M4 selective antagonist (pKi values are 8.22, 8.00, 7.51, 7.18 and 6.27 at human M2, M4, M1, M3 and M5 receptors respectively).